Dataset Information

Visceral fat reduction is positively associated with blood pressure reduction in overweight or obese males but not females: an observational study.

ABSTRACT:

Background

Visceral adiposity has been reported to play a key role in hypertension compared with other measurements of regional or general obesity. The aim of current study was to evaluate the relationship between visceral fat reduction and changes in blood pressure in a group of overweight or obese Chinese individuals.

Methods

An observational study was conducted with 168 participants (ChiCTR-OOC-17012000). Body composition, blood parameters and blood pressure were assessed at the beginning and end of the intervention. Males and females were categorized separately into quartiles according to changes in visceral fat during the intervention. Multiple linear regression models were used to assess the associations of changes in systolic and diastolic blood pressure with changes of visceral fat area, adjusted for potential confounders.

Results

Changes in visceral fat was significantly associated with systolic and diastolic blood pressure in men for systolic (β = 0.234, 95% CI: 0.103, 0.365; p = 0.001) and diastolic blood pressure (β = 0.237; 95% CI: 0.127, 0.346; p <0.001), but not in women after adjustment for the same potential confounders for systolic blood (β = - 0.003, 95% CI: - 0.260, 0.255; p = 0.984) and diastolic blood pressure (β = 0.101, 95% CI: - 0.072, 0.273; p = 0.249).

Conclusions

A positive association was observed between reduction in visceral fat and improvements in both systolic blood and diastolic blood pressures in males but not females in a 12-week meal replacement intervention.

Trial registration

The Ethics Committee of Peking University Health Science Center approved the study protocol on 6 July 2017. The authors confirm that all ongoing and related trials for this intervention were carried out following the rules of the Declaration of Helsinki of 1975 and registered (ChiCTR-OOC-17012000). http://www.chictr.org.cn/showprojen.aspx?proj=20426.

SUBMITTER: Guo X

PROVIDER: S-EPMC6617559 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Publications

Visceral fat reduction is positively associated with blood pressure reduction in overweight or obese males but not females: an observational study.

Guo Xiaohui X Xu Yifan Y He Hairong H Cai Hao H Zhang Jianfen J Li Yibin Y Yan Xinyu X Zhang Man M Zhang Na N Maddela Rolando L RL Ma Guansheng G

Nutrition & metabolism 20190710

<h4>Background</h4>Visceral adiposity has been reported to play a key role in hypertension compared with other measurements of regional or general obesity. The aim of current study was to evaluate the relationship between visceral fat reduction and changes in blood pressure in a group of overweight or obese Chinese individuals.<h4>Methods</h4>An observational study was conducted with 168 participants (ChiCTR-OOC-17012000). Body composition, blood parameters and blood pressure were assessed at th ...[more]

PMID: 31320919

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Dataset Information

Visceral fat reduction is positively associated with blood pressure reduction in overweight or obese males but not females: an observational study.

Background

Methods

Results

Conclusions

Trial registration

Publications

Visceral fat reduction is positively associated with blood pressure reduction in overweight or obese males but not females: an observational study.

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