Ontology highlight
ABSTRACT:
SUBMITTER: Rodriguez Sawicki L
PROVIDER: S-EPMC6619966 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Rodriguez Sawicki Luciana L Garcia Karina A KA Corsico Betina B Scaglia Natalia N
Cell cycle (Georgetown, Tex.) 20190615 14
Mitosis has been traditionally considered a metabolically inactive phase. We have previously shown, however, that extensive alterations in lipids occur as the cells traverse mitosis, including increased <i>de novo</i> fatty acid (FA) and phosphatidylcholine (PtdCho) synthesis and decreased lysophospholipid content. Given the diverse structural and functional properties of these lipids, we sought to study their metabolic fate and their importance for cell cycle completion. Here we show that FA an ...[more]