Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC6620588 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Li Jing J Cechova Sylvia S Wang Lina L Isakson Brant E BE Le Thu H TH Shi Weibin W
American journal of physiology. Renal physiology 20190403 6
Hypertension affects over 1 billion people worldwide and increases the risk for heart failure, stroke, and chronic kidney disease. Despite high prevalence and devastating impact, its etiology still remains poorly understood for most hypertensive cases. <i>Rcn2</i>, which encodes reticulocalbin 2, is a candidate gene for atherosclerosis that we have previously reported in mice. Here, we identified <i>Rcn2</i> as a novel regulator of blood pressure in mice. <i>Rcn2</i> was abundantly expressed in ...[more]