Air Pollution Alters Caenorhabditis elegans Development and Lifespan: Responses to Traffic-Related Nanoparticulate Matter.
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ABSTRACT:
SUBMITTER: Haghani A
PROVIDER: S-EPMC6625599 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
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Air Pollution Alters Caenorhabditis elegans Development and Lifespan: Responses to Traffic-Related Nanoparticulate Matter.
Haghani Amin A Dalton Hans M HM Safi Nikoo N Shirmohammadi Farimah F Sioutas Constantinos C Morgan Todd E TE Finch Caleb E CE Curran Sean P SP
The journals of gerontology. Series A, Biological sciences and medical sciences 20190701 8
Air pollution is a heterogeneous environmental toxicant that impacts humans throughout their life. We introduce Caenorhabditis elegans as a valuable air pollution model with its short lifespan, medium-throughput capabilities, and highly conserved biological pathways that impact healthspan. We exposed developmental and adult life stages of C. elegans to airborne nano-sized particulate matter (nPM) produced by traffic emissions and measured biological and molecular endpoints that changed in respon ...[more]
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