Ontology highlight
ABSTRACT:
SUBMITTER: Haghani A
PROVIDER: S-EPMC6625599 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Haghani Amin A Dalton Hans M HM Safi Nikoo N Shirmohammadi Farimah F Sioutas Constantinos C Morgan Todd E TE Finch Caleb E CE Curran Sean P SP
The journals of gerontology. Series A, Biological sciences and medical sciences 20190701 8
Air pollution is a heterogeneous environmental toxicant that impacts humans throughout their life. We introduce Caenorhabditis elegans as a valuable air pollution model with its short lifespan, medium-throughput capabilities, and highly conserved biological pathways that impact healthspan. We exposed developmental and adult life stages of C. elegans to airborne nano-sized particulate matter (nPM) produced by traffic emissions and measured biological and molecular endpoints that changed in respon ...[more]