The amazing HK97 fold: versatile results of modest differences.
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ABSTRACT:
SUBMITTER: Duda RL
PROVIDER: S-EPMC6626583 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
The amazing HK97 fold: versatile results of modest differences.
Duda Robert L RL Teschke Carolyn M CM
Current opinion in virology 20190308
dsDNA Bacteriophages, some dsDNA archaeal viruses and the Herpesviruses share many features including a common capsid assembly pathway and coat protein fold. The coat proteins of these viruses, which have the HK97 fold, co-assemble with a free or attached scaffolding protein and other capsid proteins into a precursor capsid, known as a procapsid or prohead. The procapsid is a metastable state that increases in stability as a result of morphological changes that occur during the dsDNA packaging r ...[more]
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