Integrated Analysis of the Altered lncRNAs and mRNAs Expression in 293T Cells after Ionizing Radiation Exposure.
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ABSTRACT:
SUBMITTER: Yang M
PROVIDER: S-EPMC6627384 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
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Integrated Analysis of the Altered lncRNAs and mRNAs Expression in 293T Cells after Ionizing Radiation Exposure.
Yang Mengmeng M Sun Yuxiao Y Xiao Changyan C Ji Kaihua K Zhang Manman M He Ningning N Wang Jinhan J Wang Qin Q Sun Zhijuan Z Wang Yan Y Du Liqing L Liu Yang Y Xu Chang C Liu Qiang Q
International journal of molecular sciences 20190618 12
Tissue and cell damage caused by ionizing radiation is often highly genotoxic. The swift repair of DNA damage is crucial for the maintenance of genomic stability and normal cell fitness. Long noncoding RNAs (lncRNAs) have been reported to play an important role in many physiological and pathological processes in cells. However, the exact function of lncRNAs in radiation-induced DNA damage has yet to be elucidated. Therefore, this study aimed to analyze the potential role of lncRNAs in radiation- ...[more]
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