Ontology highlight
ABSTRACT:
SUBMITTER: Orzabal MR
PROVIDER: S-EPMC6628922 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Orzabal Marcus R MR Lunde-Young Emilie R ER Ramirez Josue I JI Naik Vishal D VD Hillhouse Andrew A Konganti Kranti K Threadgill David W DW Ramadoss Jayanth J
Reproductive toxicology (Elmsford, N.Y.) 20190509
Binge alcohol exposure during pregnancy results in diminished vessel function and altered proteome in the maternal uterine artery. We aimed to utilize high throughput RNA-seq deep-sequencing to characterize specific effects of binge alcohol exposure during pregnancy on the uterine artery transcriptome, and gain insight into mechanisms underlying alcohol-mediated uterine artery dysfunction. Pregnant Sprague-Dawley rats assigned to Pair-Fed Control or Alcohol groups, received a once-daily orogastr ...[more]