Ontology highlight
ABSTRACT:
SUBMITTER: Ando Y
PROVIDER: S-EPMC6629254 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Ando Yoshinari Y Elkayam Elad E McPherson Robert Lyle RL Dasovich Morgan M Cheng Shang-Jung SJ Voorneveld Jim J Filippov Dmitri V DV Ong Shao-En SE Joshua-Tor Leemor L Leung Anthony K L AKL
Molecular cell 20190131 4
ADP-ribosylation refers to the addition of one or more ADP-ribose groups onto proteins. The attached ADP-ribose monomers or polymers, commonly known as poly(ADP-ribose) (PAR), modulate the activities of the modified substrates or their binding affinities to other proteins. However, progress in this area is hindered by a lack of tools to investigate this protein modification. Here, we describe a new method named ELTA (enzymatic labeling of terminal ADP-ribose) for labeling free or protein-conjuga ...[more]