Ontology highlight
ABSTRACT:
SUBMITTER: Bertazza L
PROVIDER: S-EPMC6630722 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Bertazza Loris L Barollo Susi S Mari Maria Elena ME Faccio Irene I Zorzan Maira M Redaelli Marco M Rubin Beatrice B Armanini Decio D Mian Caterina C Pezzani Raffaele R
Molecules (Basel, Switzerland) 20190612 12
<h4>Background</h4>Curcumin has numerous properties and is used in many preclinical conditions, including cancer. It has low bioavailability, while its derivative EF24 shows enhanced solubility. However, its effects have never been explored in adrenocortical tumor cell models. The efficacy of EF24 alone or combined with mitotane (reference drug for adrenocortical cancer) was evaluated in two adrenocortical tumor cell lines, SW13 and H295R.<h4>Method and results</h4>EF24 reduced cell viability wi ...[more]