Ontology highlight
ABSTRACT:
SUBMITTER: Kuo YL
PROVIDER: S-EPMC6635377 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Kuo Yao-Lung YL Jou I-Ming IM Jeng Seng-Feng SF Chu Chun-Hui CH Huang Jhy-Shrian JS Hsu Tai-I TI Hsu Tai-I TI Chang Li-Ren LR Huang Po-Wei PW Chen Jian-An JA Chou Ting-Mao TM
Scientific reports 20190716 1
Fibrosis has been considered as a major cause of capsular contracture. Hypoxia has widely emerged as one of the driving factors for fibrotic diseases. The aim of this study was to examine the association between hypoxia-induced fibrosis and breast capsular contracture formation. Fibrosis, epithelial-mesenchymal transition (EMT), expression levels of hypoxia-inducible factor-1α (HIF-1α), vimentin, fibronectin, and matrix metalloproteinase-9 (MMP-9) in tissues from patients with capsular contractu ...[more]