Ontology highlight
ABSTRACT:
SUBMITTER: Montesanto A
PROVIDER: S-EPMC6637129 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Montesanto Alberto A Bonfigli Anna Rita AR De Luca Maria M Crocco Paolina P Garagnani Paolo P Marasco Elena E Pirazzini Chiara C Giuliani Cristina C Romagnoli Fabio F Franceschi Claudio C Passarino Giuseppe G Testa Roberto R Olivieri Fabiola F Rose Giuseppina G
Scientific reports 20190717 1
Type-2 Diabetes (T2D), diabetic complications, and their clinical risk factors harbor a substantial genetic component but the genetic factors contributing to overall diabetes mortality remain unknown. Here, we examined the association between genetic variants at 21 T2D-susceptibility loci and all-cause mortality in an elderly cohort of 542 Italian diabetic patients who were followed for an average of 12.08 years. Univariate Cox regression analyses detected age, waist-to-hip ratio (WHR), glycosyl ...[more]