Ontology highlight
ABSTRACT:
SUBMITTER: Mallick H
PROVIDER: S-EPMC6637180 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Mallick Himel H Franzosa Eric A EA Mclver Lauren J LJ Banerjee Soumya S Sirota-Madi Alexandra A Kostic Aleksandar D AD Clish Clary B CB Vlamakis Hera H Xavier Ramnik J RJ Huttenhower Curtis C
Nature communications 20190717 1
Microbial community metabolomics, particularly in the human gut, are beginning to provide a new route to identify functions and ecology disrupted in disease. However, these data can be costly and difficult to obtain at scale, while amplicon or shotgun metagenomic sequencing data are readily available for populations of many thousands. Here, we describe a computational approach to predict potentially unobserved metabolites in new microbial communities, given a model trained on paired metabolomes ...[more]