Ontology highlight
ABSTRACT:
SUBMITTER: Wu Y
PROVIDER: S-EPMC6639191 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Wu Yujiao Y Shen Li L Liang Xiuming X Li Shuyan S Ma Lin L Zheng Lixin L Li Tongyu T Yu Han H Chan Hillary H Chen Chunyan C Yu Jingya J Jia Jihui J
Cancer medicine 20190530 8
Gastric cancer (GC) is one of the most common and malignant pathologies, and a significant portion of GC incidences develops from Helicobacter pylori (Hp)-induced chronic gastritis. Although the exact mechanisms of GC are complex and poorly understood, gastric carcinogenesis is a good model to investigate how inflammation and infection collaboratively promote tumorigenesis. Yes-associated protein 1 (YAP1) is the key effector of the Hippo pathway, which is silenced in most human cancers. Herein, ...[more]