Ontology highlight
ABSTRACT:
SUBMITTER: Aufinger L
PROVIDER: S-EPMC6640049 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20181127 52
Gel-based artificial organelles have been developed that enable sequence-specific and programmable localization of cell-free transcription and translation reactions inside an artificial cellular system. To this end, we utilize agarose microgels covalently modified with DNA templates coding for various functions and encapsulate them into emulsion droplets. We show that RNA signals transcribed from transcription organelles can be specifically targeted to capture organelles via hybridization to the ...[more]