Ontology highlight
ABSTRACT:
SUBMITTER: Heukers R
PROVIDER: S-EPMC6640711 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Heukers Raimond R Mashayekhi Vida V Ramirez-Escudero Mercedes M de Haard Hans H Verrips Theo C TC van Bergen En Henegouwen Paul M P PMP Oliveira Sabrina S
Antibodies (Basel, Switzerland) 20190404 2
Photodynamic therapy (PDT) is an approach that kills (cancer) cells by the local production of toxic reactive oxygen species upon the local illumination of a photosensitizer (PS). The specificity of PDT has been further enhanced by the development of a new water-soluble PS and by the specific delivery of PS via conjugation to tumor-targeting antibodies. To improve tissue penetration and shorten photosensitivity, we have recently introduced nanobodies, also known as VHH (variable domains from the ...[more]