Ontology highlight
ABSTRACT:
SUBMITTER: Fujiwara N
PROVIDER: S-EPMC6641542 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Fujiwara Naoto N Hoshida Yujin Y
Seminars in liver disease 20190325 2
Prediction of future hepatocellular carcinoma (HCC) risk in the sizable chronic liver disease population is an urgent unmet need to enable regular HCC screening for early detection. Germline deoxyribonucleic acid polymorphisms likely represent etiology-specific host factors that determine HCC susceptibility, including single nucleotide polymorphisms in <i>EGF</i>, <i>IFNL3</i>, <i>MICA</i>, and <i>TLL1</i> in hepatitis C with or without active viral infection, and <i>PNPLA3</i>, <i>TM6SF2</i>, a ...[more]