Ontology highlight
ABSTRACT:
SUBMITTER: Sabat N
PROVIDER: S-EPMC6641682 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Sabat Nazarii N Poštová Slavětínská Lenka L Klepetářová Blanka B Hocek Michal M
ACS omega 20180427 4
We developed and presented here a ferrocene-catalyzed C-H imidation of 7-deazapurines (pyrrolo[2,3-<i>d</i>]pyrimidines) with <i>N</i>-imidyl peroxyesters. The reactions occur regioselectively at position 8 in 7-deazapurines, leading to a series of 8-succinimido-, phtalimido-, or naphthalimido-7-deazapurine derivatives. Attempted hydrazinolysis of resulting 8-imidyl-7-deazapurines led to corresponding 8-amino-7-deazapurine, which was very unstable and quickly decomposed. ...[more]