Ontology highlight
ABSTRACT:
SUBMITTER: Maegawa T
PROVIDER: S-EPMC6641892 | biostudies-literature | 2018 May
REPOSITORIES: biostudies-literature
Maegawa Tomohiro T Mizui Ryota R Urasaki Miki M Fujimura Kazuma K Nakamura Akira A Miki Yasuyoshi Y
ACS omega 20180518 5
A novel approach for synthesizing chalcones by Pd-catalyzed oxidative coupling is described. This is the first report of the efficient coupling reaction of acetanilides with phenyl vinyl ketones under mild conditions. Selective C-H activation occurred next to the acetamide group to afford 2-aminochalcone derivatives. The reaction proceeded under an O<sub>2</sub> atmosphere without any chemical co-oxidants. ...[more]