Circulating Tumor Cells in Early Breast Cancer.
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ABSTRACT:
SUBMITTER: Thery L
PROVIDER: S-EPMC6649836 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
Circulating Tumor Cells in Early Breast Cancer.
Thery Laura L Meddis Alessandra A Cabel Luc L Proudhon Charlotte C Latouche Aurelien A Pierga Jean-Yves JY Bidard Francois-Clement FC
JNCI cancer spectrum 20190427 2
Circulating tumor cells (CTCs) are particularly rare in non-metastatic breast cancer, and the clinical validity of CTC detection in that clinical setting was initially not well recognized. A cytological CTC detection device (CellSearch) fulfilling the CLIA requirements for analytical validity was subsequently developed and, in 2008, we reported the first study (REMAGUS02) showing that distant metastasis-free survival was shorter in early breast cancer patients with one or more CTCs. In the past ...[more]
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