Illness Perceptions and Depression Are Associated with Health-Related Quality of Life in Youth with Inflammatory Bowel Disease.

ABSTRACT: BACKGROUND:In youth with inflammatory bowel disease (IBD), health-related quality of life (HRQOL) has been shown to be affected by individual disease factors and specific psychological factors. The innovative aim of this study is to examine the combined impact of psychological factors (illness perceptions, cognitive coping, anxiety, and depression) on HRQOL, over and above the associations of demographic and disease factors with HRQOL in youth with IBD. METHOD:Data on clinical disease activity, illness perceptions, cognitive coping, anxiety, depression, and HRQOL were prospectively collected in 262 consecutive youth (age 10-20, 46.6% male) with confirmed IBD. Multiple linear regression analyses tested the associations of demographic, disease, and psychological variables with HRQOL in separate groups for Crohn's disease (CD; N =?147) and ulcerative colitis and IBD unclassified (UC/IBD-U; N =?115), using age-specific validated instruments. RESULTS:In both disease groups, more negative illness perceptions (ß?=?-?.412; ß?=?-?.438, p?

SUBMITTER: Stapersma L 

PROVIDER: S-EPMC6652166 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature