Ontology highlight
ABSTRACT:
SUBMITTER: Ho C
PROVIDER: S-EPMC6653754 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Ho Chiakang C Gao Ya Y Zheng Danning D Liu Yanjun Y Shan Shengzhou S Fang Bin B Zhao Yixuan Y Song Dingzhong D Zhang Yifan Y Li Qingfeng Q
Journal of cellular and molecular medicine 20190529 8
Obesity and its associated metabolic disorders such as diabetes, hepatic steatosis and chronic heart diseases are affecting billions of individuals. However there is no satisfactory drug to treat such diseases. In this study, we found that alisol A, a major active triterpene isolated from the Chinese traditional medicine Rhizoma Alismatis, could significantly attenuate high-fat-diet-induced obesity. Our biochemical detection demonstrated that alisol A remarkably decreased lipid levels, alleviate ...[more]