Ontology highlight
ABSTRACT:
SUBMITTER: Mercatelli D
PROVIDER: S-EPMC6657420 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Mercatelli Daniele D Ray Forest F Giorgi Federico M FM
Frontiers in genetics 20190718
Cancer is a disease often characterized by the presence of multiple genomic alterations, which trigger altered transcriptional patterns and gene expression, which in turn sustain the processes of tumorigenesis, tumor progression, and tumor maintenance. The links between genomic alterations and gene expression profiles can be utilized as the basis to build specific molecular tumorigenic relationships. In this study, we perform pan-cancer predictions of the presence of single somatic mutations and ...[more]