Ontology highlight
ABSTRACT:
SUBMITTER: Kim H
PROVIDER: S-EPMC6658535 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Kim Hyun H Fukutomi Yasuo Y Nakajima Chie C Kim Youn Uck YU Mori Shigetarou S Shibayama Keigo K Nakata Noboru N Suzuki Yasuhiko Y
Scientific reports 20190725 1
Leprosy, an important infectious disease in humans caused by Mycobacterium leprae (Mle), remains endemic in many countries. Notably, the pathogen cannot be cultured in vitro, except in mouse footpads in vivo. The molecular basis of these characteristics and the mechanisms remain unknown. Consequently, analysis of Mle growth and survival is urgently needed to develop novel therapies against leprosy, including rapid, simple, and specific methods to detect infection. Here, we demonstrated the funct ...[more]