Ontology highlight
ABSTRACT:
SUBMITTER: Budau L
PROVIDER: S-EPMC6658576 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Budau Laura L Wilhelm Christian C Moll Roland R Jäkel Jörg J Hirt Carsten C Dölken Gottfried G Maschmeyer Georg G Neubauer Ellen E Strauch Konstantin K Burchert Andreas A Herold Michael M Neubauer Andreas A
Journal of cancer research and clinical oncology 20190704 8
<h4>Background</h4>First-line rituximab therapy together with chemotherapy is the standard care for patients with advanced follicular B-cell lymphoma, as rituximab together with chemotherapy prolongs progression-free and overall survival (Herold et al. 2007; Marcus et al. 2005). However, as not all patient subgroups benefit from combined immuno-chemotherapy, we asked whether the microenvironment may predict benefit from rituximab-based therapy.<h4>Design</h4>To address this question, we performe ...[more]