Ontology highlight
ABSTRACT:
SUBMITTER: Banerjee H
PROVIDER: S-EPMC6658674 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Banerjee Hiren H Knoblach Barbara B Rachubinski Richard A RA
Life science alliance 20190724 4
Trypanosomatid parasites are infectious agents for diseases such as African sleeping sickness, Chagas disease, and leishmaniasis that threaten millions of people, mostly in the emerging world. Trypanosomes compartmentalize glycolytic enzymes to an organelle called the glycosome, a specialized peroxisome. Functionally intact glycosomes are essential for trypanosomatid viability, making glycosomal proteins as potential drug targets against trypanosomatid diseases. Peroxins (Pex), of which Pex3 is ...[more]