Ontology highlight
ABSTRACT:
SUBMITTER: Vinue L
PROVIDER: S-EPMC6658789 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Vinué Laura L Sater Mohamad R A MRA Herriott Ian I Huntley Miriam H MH Jacoby George A GA Hooper David C DC
Antimicrobial agents and chemotherapy 20190725 8
In a previous study, mutants with enhanced ciprofloxacin resistance (Cip<sup>r</sup>) were selected from <i>Escherichia coli</i> J53/pMG252 carrying <i>qnrA1</i> Strain J53 Cip<sup>r</sup> 8-2 showed an increase in the copy number and transcription level of <i>qnrA1</i> We sequenced the plasmids on Illumina and MinION platforms. Parental plasmid pMG252 and plasmid pMG252A from strain J53 Cip<sup>r</sup> 8-2 were almost identical, except for the region containing <i>qnrA1</i> that in pMG252A cont ...[more]