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MC4R and ENPP1 gene polymorphisms and their implication in maternal and neonatal risk for obesity.


ABSTRACT: The aims of this study were to establish the role of MC4Rrs17782313 and ENPP1rs1044498 gene polymorphisms on pre-pregnancy BMI and the newborn's status. We performed a cross-sectional study on 185 mothers and their offspring. The groups were divided into: control group- underweight or normal mothers with BMIinitial?

SUBMITTER: Marginean C 

PROVIDER: S-EPMC6659701 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

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MC4R and ENPP1 gene polymorphisms and their implication in maternal and neonatal risk for obesity.

Mărginean Claudiu C   Mărginean Cristina Oana CO   Iancu Mihaela M   Meliț Lorena Elena LE   Tripon Florin F   Bănescu Claudia C  

Scientific reports 20190726 1


The aims of this study were to establish the role of MC4Rrs17782313 and ENPP1rs1044498 gene polymorphisms on pre-pregnancy BMI and the newborn's status. We performed a cross-sectional study on 185 mothers and their offspring. The groups were divided into: control group- underweight or normal mothers with BMI<sub>initial</sub> < 25 kg/m<sup>2</sup> (n<sub>1</sub> = 134) and study group-overweight/obese mothers with BMI<sub>initial</sub> ≥ 25 kg/m<sup>2</sup> (n<sub>2</sub> = 51). All subjects und  ...[more]

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