Ontology highlight
ABSTRACT:
SUBMITTER: Gunay KA
PROVIDER: S-EPMC6660351 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20190611 29
There is a growing interest in materials that can dynamically change their properties in the presence of cells to study mechanobiology. Herein, we exploit the 365 nm light mediated [4+4] photodimerization of anthracene groups to develop cytocompatible PEG-based hydrogels with tailorable initial moduli that can be further stiffened. A hydrogel formulation that can stiffen from 10 to 50 kPa, corresponding to the stiffness of a healthy and fibrotic heart, respectively, was prepared. This system was ...[more]