Ontology highlight
ABSTRACT:
SUBMITTER: Klass SH
PROVIDER: S-EPMC6660407 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Klass Sarah H SH Truxal Ashley E AE Fiala Tahoe A TA Kelly Joseph J Nguyen Dang D Finbloom Joel A JA Wemmer David E DE Pines Alexander A Francis Matthew B MB
Angewandte Chemie (International ed. in English) 20190611 29
The development of sensitive and chemically selective MRI contrast agents is imperative for the early detection and diagnosis of many diseases. Conventional responsive contrast agents used in <sup>1</sup> H MRI are impaired by the high abundance of protons in the body. <sup>129</sup> Xe hyperCEST NMR/MRI comprises a highly sensitive complement to traditional <sup>1</sup> H MRI because of its ability to report specific chemical environments. To date, the scope of responsive <sup>129</sup> Xe NMR ...[more]