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Histological data of axons, astrocytes, and myelin in deep subcortical white matter populations.

ABSTRACT: This immunohistochemistry dataset contains the main structures in deep subcortical white matter (axons, astrocytes, and myelinated axons) in a representative cohort of an ageing population. A set of samples from 90 subjects of the Cognitive Function and Ageing Study (CFAS) were analysed, stratified into three groups of 30 subjects each, in relation to the presence of age-associated deep subcortical lesions. High-resolution microscopy data enables the extraction of valuable information, such as volume fractions, for the construction and validation of diffusion MRI (dMRI) models. The dataset provided here was used in Coelho et al. [1].

SUBMITTER: Coelho S

PROVIDER: S-EPMC6660516 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature

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Histological data of axons, astrocytes, and myelin in deep subcortical white matter populations.

Coelho Santiago S Pozo Jose M JM Costantini Marina M Highley J Robin JR Mozumder Meghdoot M Simpson Julie E JE Ince Paul G PG Frangi Alejandro F AF

Data in brief 20190306

This immunohistochemistry dataset contains the main structures in deep subcortical white matter (axons, astrocytes, and myelinated axons) in a representative cohort of an ageing population. A set of samples from 90 subjects of the Cognitive Function and Ageing Study (CFAS) were analysed, stratified into three groups of 30 subjects each, in relation to the presence of age-associated deep subcortical lesions. High-resolution microscopy data enables the extraction of valuable information, such as v ...[more]

PMID: 31372422

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