Ontology highlight
ABSTRACT:
SUBMITTER: Nagata Y
PROVIDER: S-EPMC6661863 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Nagata Yuuya Y Takeda Ryohei R Suginome Michinori M
ACS central science 20190703 7
Use of chiral solvents in asymmetric synthesis as a sole source of enantioselection remains largely unexplored in organic synthesis. We found that the use of a helical macromolecular catalyst of which helical chirality is dynamically formed in chiral solvents allowed several mechanistically different reactions to proceed with high enantioselectivity. In this system, the chirality of the solvent, such as limonene, induces a configurational imbalance to the helical macromolecular scaffold of the c ...[more]