Ontology highlight
ABSTRACT:
SUBMITTER: Cheng Y
PROVIDER: S-EPMC6663092 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Cheng Yichen Y Dai James Y JY Wang Xiaoyu X Kooperberg Charles C
Biometrics 20180612 4
Copy number variation (CNV) of DNA plays an important role in the development of many diseases. However, due to the irregularity and sparsity of the CNVs, studying the association between CNVs and a disease outcome or a trait can be challenging. Up to now, not many methods have been proposed in the literature for this problem. Most of the current researchers reply on an ad hoc two-stage procedure by first identifying CNVs in each individual genome and then performing an association test using th ...[more]