Ontology highlight
ABSTRACT:
SUBMITTER: Deotale VD
PROVIDER: S-EPMC6664147 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Deotale Vinod D VD Katiya Manish M MM Dhonde Madhukar G MG
Heliyon 20190725 7
Synthesis of thiobarbituric acids by the reaction of 1,3-disubstituted thioureas and malonic acid in acetyl chloride-acetic acid medium and synthesis of cyclized pyrimidin-7-one by the interaction of 1-(2-hydroxyethyl)-aryl thioureas, with malonic acid in <i>p</i>-tolyl sulphonic acid and acetyl chloride-acetic acid medium at room temperature stirring has been reported. The present protocol is highly eco-friendly alternative to existing methods, reduces the excess use of acetyl chloride and puri ...[more]