Ontology highlight
ABSTRACT:
SUBMITTER: Numano T
PROVIDER: S-EPMC6676138 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Numano Takamasa T Higuchi Hitomi H Alexander David B DB Alexander William T WT Abdelgied Mohamed M El-Gazzar Ahmed M AM Saleh Dina D Takase Hiroshi H Hirose Akihiko A Naiki-Ito Aya A Suzuki Shugo S Takahashi Satoru S Tsuda Hiroyuki H
Cancer science 20190725 8
Multi-walled carbon nanotube-7 (MWCNT-7) fibers are biopersistent and have a structure similar to asbestos. MWCNT-7 has been shown to induce malignant mesothelioma when administered by intrascrotal or intraperitoneal injection in rats and mice, and an inhalation study demonstrated that rats exposed to respirable MWCNT-7 developed lung tumors. MWCNT-N, which is similar to MWCNT-7, was shown to induce both lung tumors and malignant mesothelioma in rats when administered by trans-tracheal intrapulm ...[more]