Construction of subtype-specific prognostic gene signatures for early-stage non-small cell lung cancer using meta feature selection methods.
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ABSTRACT:
SUBMITTER: Liu C
PROVIDER: S-EPMC6676737 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Construction of subtype-specific prognostic gene signatures for early-stage non-small cell lung cancer using meta feature selection methods.
Liu Chunshui C Wang Linlin L Wang Tianjiao T Tian Suyan S
Oncology letters 20190704 3
Feature selection in the framework of meta-analyses (meta feature selection), combines meta-analysis with a feature selection process and thus allows meta-analysis feature selection across multiple datasets. In the present study, a meta feature selection procedure that fitted a multiple Cox regression model to estimate the effect size of a gene in individual studies and to identify the overall effect of the gene using a meta-analysis model was proposed. The method was used to identify prognostic ...[more]
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