Ontology highlight
ABSTRACT:
SUBMITTER: Tang B
PROVIDER: S-EPMC7874010 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Tang Binhua B Wang Yuqi Y Chen Yu Y Li Ming M Tao Yongfeng Y
Frontiers in cell and developmental biology 20210108
Carcinoma diagnosis and prognosis are still hindered by the lack of effective prediction model and integration methodology. We proposed a novel feature selection with orthogonal regression (FSOR) method to resolve predictor selection and performance optimization. Functional enrichment and clinical outcome analyses with multi-omics information validated the method's robustness in the early-stage prognosis of lung adenocarcinoma. Furthermore, compared with the classic least absolute shrinkage and ...[more]