Ontology highlight
ABSTRACT:
SUBMITTER: van Veldhuisen E
PROVIDER: S-EPMC6679311 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
van Veldhuisen Eran E van den Oord Claudia C Brada Lilly J LJ Walma Marieke S MS Vogel Jantien A JA Wilmink Johanna W JW Del Chiaro Marco M van Lienden Krijn P KP Meijerink Martijn R MR van Tienhoven Geertjan G Hackert Thilo T Wolfgang Christopher L CL van Santvoort Hjalmar H Groot Koerkamp Bas B Busch Olivier R OR Molenaar I Quintus IQ van Eijck Casper H CH Besselink Marc G MG
Cancers 20190712 7
Locally advanced pancreatic cancer (LAPC) has several definitions but essentially is a nonmetastasized pancreatic cancer, in which upfront resection is considered not beneficial due to extensive vascular involvement and consequent high chance of a nonradical resection. The introduction of FOLFIRINOX chemotherapy and gemcitabine-nab-paclitaxel (gem-nab) has had major implications for the management and outcome of patients with LAPC. After 4-6 months induction chemotherapy, the majority of patient ...[more]