Locally Advanced Pancreatic Cancer: A Review of Local Ablative Therapies.
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ABSTRACT:
SUBMITTER: Ruarus A
PROVIDER: S-EPMC5789366 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
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Locally Advanced Pancreatic Cancer: A Review of Local Ablative Therapies.
Ruarus Alette A Vroomen Laurien L Puijk Robbert R Scheffer Hester H Meijerink Martijn M
Cancers 20180110 1
Pancreatic cancer is typically characterized by its aggressive tumor growth and dismal prognosis. Approximately 30% of patients with pancreatic cancer present with locally advanced disease, broadly defined as having a tumor-to-artery interface >180°, having an unreconstructable portal vein or superior mesenteric vein and no signs of metastatic disease. These patients are currently designated to palliative systemic chemotherapy, though median overall survival remains poor (approximately 11 months ...[more]
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