Ontology highlight
ABSTRACT:
SUBMITTER: Avery MB
PROVIDER: S-EPMC6679866 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Avery Michael B MB Belanger Brooke L BL Bromley Amy A Sen Arindom A Mitha Alim P AP
Stem cells international 20190722
Several studies have demonstrated a potential interaction between mesenchymal stem cells (MSCs) and saccular aneurysms. In this study, we sought to determine whether allogenic bone marrow-derived MSCs had the ability to prevent aneurysm formation in a known rabbit elastase aneurysm model. MSCs were injected intravenously in experimental rabbits at the time of surgical creation and two weeks postcreation and compared with control rabbits receiving vehicle injection. Angiography was used to compar ...[more]