Ontology highlight
ABSTRACT:
SUBMITTER: Wiewiorka M
PROVIDER: S-EPMC6680061 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Wiewiórka Marek M Szmurło Agnieszka A Kuśmirek Wiktor W Gambin Tomasz T
GigaScience 20190801 8
<h4>Background</h4>Depth of coverage calculation is an important and computationally intensive preprocessing step in a variety of next-generation sequencing pipelines, including the analysis of RNA-sequencing data, detection of copy number variants, or quality control procedures.<h4>Results</h4>Building upon big data technologies, we have developed SeQuiLa-cov, an extension to the recently released SeQuiLa platform, which provides efficient depth of coverage calculations, reaching >100× speedup ...[more]