Ontology highlight
ABSTRACT:
SUBMITTER: Taylor CG
PROVIDER: S-EPMC6680264 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Taylor Christopher G P CG Cullen William W Collier Olivia M OM Ward Michael D MD
Chemistry (Weinheim an der Bergstrasse, Germany) 20161123 1
We have performed a systematic investigation of the effects of guest flexibility on their ability to bind in the cavity of a coordination cage host in water, using two sets of isomeric aliphatic ketones that differ only in the branching patterns of their alkyl chains. Apart from the expected increase in binding strength for C<sub>9</sub> over C<sub>7</sub> ketones associated with their greater hydrophobic surface area, within each isomeric set there is a clear inverse correlation between binding ...[more]