Ontology highlight
ABSTRACT:
SUBMITTER: Bojanowski J
PROVIDER: S-EPMC6681191 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20190715 14
In this manuscript, a novel, decarboxylative Michael reaction between α-substituted azlactones and chromone-3-carboxylic acids is described. The reaction proceeds in a sequence Michael addition followed by decarboxylative deprotonation, and it results in the formation of chromanones bearing an azlactone structural unit. The possibility of transforming an azlactone moiety into a protected α,α-disubstituted α-amino acid derivative is also demonstrated. ...[more]