Ontology highlight
ABSTRACT:
SUBMITTER: Stewart SH
PROVIDER: S-EPMC6684329 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Stewart Scott H SH Walitzer Kimberly S KS Blanco Javier J Swiatek Denise D Paine Hughes Linda L Quiñones-Lombraña Adolfo A Shyhalla Kathleen K
Journal of substance abuse treatment 20190504
Medication-assisted behavior treatment for alcohol use disorder (AUD) holds promise to enhance the efficacy of medication and of behavior therapy when administered individually. The present study examines the treatment benefit of combined outpatient naltrexone (NTX) treatment with Alcoholics Anonymous Facilitation (AAF) behavior therapy, in the context of OPRM1 genotype. The minor OPRM1 Asp40 G-allele has been associated with greater positive reinforcing effects of alcohol consumption and greate ...[more]