Tau positron emission tomography imaging in C9orf72 repeat expansion carriers.
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ABSTRACT:
SUBMITTER: Ly CV
PROVIDER: S-EPMC6684398 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Tau positron emission tomography imaging in C9orf72 repeat expansion carriers.
Ly C V CV Koenig L L Christensen J J Gordon B B Beaumont H H Dahiya S S Chen J J Su Y Y Nelson B B Jockel-Balsarotti J J Drain C C Jerome G G Morris J C JC Fagan A M AM Harms M B MB Benzinger T L S TLS Miller T M TM Ances B M BM
European journal of neurology 20190325 9
<h4>Background and purpose</h4>AV-1451 (<sup>18</sup> F-AV-1451, flortaucipir) positron emission tomography was performed in C9orf72 expansion carriers to assess tau accumulation and disease manifestation.<h4>Methods</h4>Nine clinically characterized C9orf72 expansion carriers and 18 age- and gender- matched cognitively normal individuals were psychometrically evaluated and underwent tau positron emission tomography imaging. The regional AV-1451 standard uptake value ratios from multiple brain r ...[more]
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