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Abundance of gut Prevotella at baseline and metabolic response to barley prebiotics.


ABSTRACT: PURPOSE:We previously showed that short-term intervention with barley kernel bread (BKB) improved glucose tolerance. However, glucose tolerance was not improved in a subset of individuals (non-responders) who were characterized by a low Prevotella/Bacteroides ratio. The purpose of the present study was to investigate if the baseline Prevotella/Bacteroides ratio can be used to stratify metabolic responders and non-responders to barley dietary fiber (DF). METHODS:Fecal samples were collected from 99 healthy humans with BMI?

SUBMITTER: Sandberg J 

PROVIDER: S-EPMC6689319 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Abundance of gut Prevotella at baseline and metabolic response to barley prebiotics.

Sandberg Jonna J   Kovatcheva-Datchary Petia P   Björck Inger I   Bäckhed Fredrik F   Nilsson Anne A  

European journal of nutrition 20180725 6


<h4>Purpose</h4>We previously showed that short-term intervention with barley kernel bread (BKB) improved glucose tolerance. However, glucose tolerance was not improved in a subset of individuals (non-responders) who were characterized by a low Prevotella/Bacteroides ratio. The purpose of the present study was to investigate if the baseline Prevotella/Bacteroides ratio can be used to stratify metabolic responders and non-responders to barley dietary fiber (DF).<h4>Methods</h4>Fecal samples were  ...[more]

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