Ontology highlight
ABSTRACT:
SUBMITTER: Leon-Mimila P
PROVIDER: S-EPMC6266693 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
León-Mimila Paola P Villamil-Ramírez Hugo H López-Contreras Blanca E BE Morán-Ramos Sofía S Macias-Kauffer Luis R LR Acuña-Alonzo Víctor V Del Río-Navarro Blanca E BE Salmerón Jorge J Velazquez-Cruz Rafael R Villarreal-Molina Teresa T Aguilar-Salinas Carlos A CA Canizales-Quinteros Samuel S
Nutrients 20181101 11
Genome-wide association studies (GWAS) have identified copy number variants (CNVs) associated with obesity in chromosomal regions 1p31.1, 10q11.22, 11q11, 16p12.3, and recently 1p21.1, which contains the salivary amylase gene (<i>AMY1</i>). Recent evidence suggests this enzyme may influence gut microbiota composition through carbohydrate (mainly starch) degradation. The role of these CNVs in obesity has been scarcely explored in the Latino population, and thus the aim of our study was to evaluat ...[more]