Calcium phosphate coated 3D printed porous titanium with nanoscale surface modification for orthopedic and dental applications.

ABSTRACT: This study aims to improve the interfacial bonding between the osseous host tissue and the implant surface through the application of doped calcium phosphate (CaP) coating on 3D printed porous titanium. Porous titanium (Ti) cylinders with 25% volume porosity were fabricated using Laser Engineered Net Shaping (LENS™), a commercial 3D Printing technique. The surface of these 3D printed cylinders was modified by growing TiO₂ nanotubes first, followed by a coating of with Sr²⁺ and Si⁴⁺ doped bioactive CaP ceramic in simulated body fluid (SBF). Doped CaP coated implants were hypothesized to show enhanced early stage bone tissue integration. Biological properties of these implants were investigated in vivo using a rat distal femur model after 4 and 10 week

SUBMITTER: Bose S 

PROVIDER: S-EPMC6690623 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature