Ontology highlight
ABSTRACT:
SUBMITTER: Pratt-Riccio LR
PROVIDER: S-EPMC6690721 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Pratt-Riccio Lilian Rose LR Baptista Bárbara de Oliveira BO Torres Vanessa Rodrigues VR Bianco-Junior Cesare C Perce-Da-Silva Daiana de Souza DS Riccio Evelyn Kety Pratt EKP Lima-Junior Josué da Costa JDC Totino Paulo Renato Rivas PRR Cassiano Gustavo Capatti GC Storti-Melo Luciane Moreno LM Machado Ricardo Luiz Dantas RLD de Oliveira-Ferreira Joseli J Banic Dalma Maria DM Carvalho Leonardo José de Moura LJM Daniel-Ribeiro Cláudio Tadeu CT
Memorias do Instituto Oswaldo Cruz 20190812
<h4>Background</h4>The central repetitive region (CRR) of the Plasmodium vivax circumsporozoite surface protein (CSP) is composed of a repetitive sequence that is characterised by three variants: VK210, VK247 and P. vivax-like. The most important challenge in the treatment of P. vivax infection is the possibility of differential response based on the parasite genotype.<h4>Objectives</h4>To characterise the CSP variants in P. vivax isolates from individuals residing in a malaria-endemic region in ...[more]