Ontology highlight
ABSTRACT:
SUBMITTER: Soares LA
PROVIDER: S-EPMC3987980 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Journal of immunology research 20140227
The diversity of MSP1 in both Plasmodium falciparum and P. vivax is presumed be associated to parasite immune evasion. In this study, we assessed genetic diversity of the most variable domain of vaccine candidate N-terminal PvMSP1 (Block 2) in field isolates of Manaus. Forty-seven blood samples the polymorphism of PvMSP1 Block 2 generates four fragment sizes. In twenty-eight of them, sequencing indicated seven haplotypes of PvMSP1 Block 2 circulating among field isolates. Evidence of striking ex ...[more]