Ontology highlight
ABSTRACT:
SUBMITTER: Sakkas LI
PROVIDER: S-EPMC6691125 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Frontiers in pharmacology 20190806
Psoriasis, an inflammatory skin disease, and psoriatic arthritis (PsA), an inflammatory arthritis, share clinical, genetic, and pathogenic factors and may be summed as one disease, the psoriatic disease. Interleukin (IL)-17 plays a major role in the development of both psoriasis and PsA. IL-23 is important in the proliferation and maintenance of IL-17, and therefore, cytokines of the IL-23/IL-17 axis attracted much interest as therapeutic targets in psoriasis and PsA. Therapeutic agents targetin ...[more]